Perfil microbiológico de hemoculturas em uma Unidade de Terapia Intensiva Neonatal do Distrito Federal

Abstract

Introduction: neonatal infections are responsible for a high rate of mortality, morbidity and increase in the period and cost of hospitali‑zation. Signs are subtle and can be easily confused, they have rapid evolution, and trained staff is needed for proper identification and tre‑atment. Blood culture is currently the standard for identifying bloods‑tream infections. Objectives: To describe the incidence, sensitivity and resistance pro‑file of microorganisms isolated from blood cultures carried out in a Neonatal Intensive Care Unit of a General Hospital of the Federal Dis‑trict in a period of one year (January 01 to December 31, 2015). Method: this is a epidemiological study of a quantitative approach car‑ried out by means of Electronic Record Research after approval by the Research Ethics Board. Results and discussion: 86 medical records and 212 blood cultures were analyzed, two were excluded from the study according to esta‑blished criteria. 44 (20,9%) blood cultures have a positive result. The most incidence microorganisms belonged to the group of gram positive bacteria (65,8%) followed by yeasts (22,7%) and gram negative bacteria (11,3%). The resistance profile of the most incidence microorganisms showed a higher resistance of Staphylococcus epidermidis (n = 18) to β‑lactams (100%), Aminoglycosides (80,5%), Quinolones (72,2%) and Macrolides (61,1%); Enterococcus faecalis (n = 4) showed resistance to Macrolides and Streptogramina (75%) and Rifampicin (50%). Conclusion: in order to have a prudent and safer use of antibiotic the‑rapy, knowledge about the microbiological profile of the unit is necessa‑ry in order to avoid resistance and better target control and prevention actions.