Trombocitopenia induzida por heparina de baixo peso molecular em pós-operatório de cirurgia não cardíaca: coorte prospectiva

Abstract

Heparin-induced thrombocytopenia (HIT) is a prothrombotic adverse reaction. The aim of the study is to identify the occurrence of low molecular weight heparin-induced thrombocytopenia in patients undergoing non-cardiac surgery at a Tertiary Hospital in the Federal District. Methodology: this is a prospective single-arm cohort study, withinclusion for convenience with a STROBE Statement design. The study was carried outfrom August to December 2019. Results: 46 eligible surgical patients were selected, whowere exposed to low molecular weight heparin anticoagulation and obtained plateletcount monitoring during exposure. The occurrence of thrombocytopenia with platelet reduction <150,000mm³ was 19.56% in the perioperative period, related too ther clinical causes. All cases had a score of 4Ts(<4points), HIT being unlikely. Conclusion: HIT is a rare immunohematological syndrome in patient susing low molécular weight heparin in the postoperative periodo fnon-cardiac surgery.